|
Symbol Name ID |
Cnr1
cannabinoid receptor 1 MGI:104615 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | EEG abnormality |
Delusion |
Schizophrenia |
Hallucinations |
Negativism |
Social and occupational deterioration |
| Disease(s) Associated with CNR1 | ||||||
| schizophrenia |
| Mouse Phenotypes | nervous system phenotype |
increased susceptibility to pharmacologically induced seizures |
increased susceptibility to neuronal excitotoxicity |
abnormal axon fasciculation |
abnormal neuronal precursor proliferation |
increased susceptibility to ischemic brain injury |
increased cerebral infarct size |
abnormal nervous system morphology |
abnormal cerebral cortex morphology |
abnormal nervous system development |
abnormal nervous system physiology |
abnormal neuron physiology |
abnormal synaptic plasticity |
abnormal excitatory postsynaptic potential |
abnormal inhibitory postsynaptic currents |
enhanced long-term potentiation |
absent long-term depression |
reduced long-term depression |
decreased synaptic depression |
abnormal paired-pulse facilitation |
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| Availability | Mouse Genotype | ||||||||||||||||||||
| Cnr1tm1.1Kpm/Cnr1tm1.1Kpm | |||||||||||||||||||||
| Cnr1tm1.1Ltz/Cnr1tm1.1Ltz | * | ||||||||||||||||||||
| Cnr1tm1Dgen/Cnr1tm1Dgen | * | ||||||||||||||||||||
| Cnr1tm1Map/Cnr1tm1Map | |||||||||||||||||||||
| Cnr1tm1Ojm/Cnr1tm1Ojm | |||||||||||||||||||||
| Cnr1tm2Ltz/Cnr1tm2Ltz | |||||||||||||||||||||
| Cnr1tm1.1Ltz/Cnr1+ | |||||||||||||||||||||
| Cnr1tm1Map/Cnr1+ | |||||||||||||||||||||
| Cnr1tm1.2Ltz/Cnr1tm1.2Ltz Tg(Camk2a-cre)2Gsc/0 (conditional) |
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| Cnr1tm1.2Ltz/Cnr1tm1.2Ltz Tg(Camk2a-cre)2Gsc/? (conditional) |
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| Cnr1tm1.2Ltz/Cnr1tm1.2Ltz (conditional) | |||||||||||||||||||||
| Cnr1tm1.2Ltz/Cnr1tm1.2Ltz Neurod6tm1(cre)Kan/Neurod6+ (conditional) |
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| Cnr1tm1.2Ltz/Cnr1tm1.2Ltz Tg(dlx5a-cre)1Mekk/? (conditional) |
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| Cnr1tm2Ltz/Cnr1tm2.1Ltz Neurod6tm1(cre)Kan/Neurod6+ (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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